مقالات علمی

با معجزات عجیب قارچ گانودرما آشنا شوید

 اسامی دیگر: رِیشی (Reishi) یا لین ژی (Ling Zhi)

نام علمی Ganoderma lucidum (W.Curt.:Fr.) P. Karst.

قارچ گانودرما خواص بسیار عجیبی دارد . مصرف این قارچ از گذشته های بسیار دور در میان مردم مشرق زمین رایج  و مورد مصرف روزانه این مردم بوده . چند سالی است که این قارچ در ایران توسط ما یعنی شرکت نسیم سبز دانش  به صورت اختصاصی در دست تولید است و هر روزه بر مشتریان مصرف این نوع قارچ ها اضافه می شود . با توجه به افزایش سوالات شما کاربران عزیز بر این شدیم تا مطالبی را در مورد خواص بسیار زیاد این نوع قارچ دارویی برای شما تهیه کنیم تا از آن استفاده نمائید

گانودرمامهمترین قارچ دارویی جهان است که گاهی با عنوان قارچ جاودانگی (Mushroom of Immortality) یا قارچ مقدس (spirit mushroom) شناخته می شود. استفاده از این قارچ از هزاران سال پیش در چین و ژاپن و ســایر کشور هــای آســیایی در طب سنتی و همـچنـین تحقیقـات علمـی روز از جمله : تقویت سیستم ایمنی انواع سرطان از جمله سرطان پروستات، سرطان سینه ، سرطان روده ، سرطان مثانه ، سرطان ریه ، سرطان کلیه ، سرطان تخمدان ، سرطان دهانه رهم ، آنتی اکسیدان ، آسم و برونشیت ، بیماری های قلبی و عروقی ، فشار خون ، کلسترول بالا ، چربی سوزی ، قند خون ، بیماری های کلیوی ، بیماری های کبد ، کبد چرب، ایدز ، خستگی ، بیخوابی ، زگیل تناسلی ، تبخال تناسلی ، هپاتیت ، رماتیسم استفاده شده است.

 

 

Bach, E., Hi, E., Martins, A., Nascimento, P. & Wadt, N. (2018) Hypoglicemic and Hypolipedimic Effects of Ganoderma lucidum in Streptozotocin-Induced Diabetic Rats. Medicines 5(3): 78.

Bao-xue, Y., Li-min, S., Li-ying, L., Hong, Z. & Ruo-yun, C. (2017) Ganoderma triterpenes slow cyst growth in polycystic kidney disease. Chinese Journal of Pharmacology and Toxicology 31(10): 1006-1007.

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Donatini, B. (2014) Control of oral human papillomavirus (HPV) by medicinal mushrooms, Trametes versicolor and Ganoderma lucidum: a preliminary clinical trial. International Journal of Medicinal Mushrooms 16(5).

El-Mekkawy, S., Meselhy, M.R., Nakamura, N., Tezuka, Y., Hattori, M., Kakiuchi, N., Shimotohno, K., Kawahata, T. & Otake, T. (1998) Anti-HIV-1 and anti-HIV-1-protease substances from Ganoderma lucidum. Phytochemistry 49(6): 1651-1657.

El Dine, R.S., El Halawany, A.M., Ma, C.-M. & Hattori, M. (2008) Anti-HIV-1 protease activity of lanostane triterpenes from the vietnamese mushroom Ganoderma colossum. Journal of Natural Products 71(6): 1022-1026.

Eo, S.-K., Kim, Y.-S., Lee, C.-K. & Han, S.-S. (2000) Possible mode of antiviral activity of acidic protein bound polysaccharide isolated from Ganoderma lucidum on herpes simplex viruses. Journal of Ethnopharmacology 72(3): 475-481.

FLÓREZ-SAMPEDRO, L., Zapata, W., Orozco, L.P., Mejía, A.I., Arboleda, C. & Rugeles, M.T. (2016) In vitro anti-HIV-1 activity of the enzymatic extract enriched with laccase produced by the fungi Ganoderma sp. and Lentinus sp. Vitae 23(2): 109-118.

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Gao, Y., Chen, G., Dai, X., Ye, J. & Zhou, S. (2004b) A phase I/II study of ling zhi mushroom Ganoderma lucidum (W. Curt.: Fr.) Lloyd (Aphyllophoromycetideae) extract in patients with coronary heart disease. International Journal of Medicinal Mushrooms 6(4).

Gao, Y., Lan, J., Dai, X., Ye, J. & Zhou, S. (2004c) A phase I/II study of Ling Zhi mushroom Ganoderma lucidum (W. Curt.: Fr.) Lloyd (Aphyllophoromycetideae) extract in patients with type II diabetes mellitus. International Journal of Medicinal Mushrooms 6(1).

Gao, Y., Zhou, S., Chen, G., Dai, X., Ye, J. & Gao, H. (2002) A Phase I/II Study of a Ganoderma lucidum (Curt.: Fr.) P. Karst.(Ling Zhi, Reishi Mushroom) extract in patients with chronic hepatitis В. International Journal of Medicinal Mushrooms 4(4).

Gill, B.S., Navgeet & Kumar, S. (2017) Ganoderma lucidum targeting lung cancer signaling: A review. Tumor Biology 39(6): 1010428317707437.

Han, X.-Q., Chan, B.C.L., Yu, H., Yang, Y.-H., Hu, S.-Q., Ko, C.-H., Dong, C.-X., Wong, C.-K., Shaw, P.-C. & Fung, K.-P. (2012) Structural characterization and immuno-modulating activities of a polysaccharide from Ganoderma sinense. International Journal of Biological Macromolecules 51(4): 597-603.

Hijikata, Y., Yamada, S. & Yasuhara, A. (2007) Herbal mixtures containing the mushroom Ganoderma lucidum improve recovery time in patients with herpes genitalis and labialis. The Journal of Alternative and Complementary Medicine 13(9): 985-987.

Hu, R., Guo, W., Huang, Z., Li, L., Liu, B. & Lv, X. (2018) Extracts of Ganoderma lucidum attenuate lipid metabolism and modulate gut microbiota in high-fat diet fed rats. Journal of Functional Foods 46: 403-412.

Huang, C., Chen, S., Lai, H., Lin, Y., Su, C., Wu, S., Chang, C., Tsao, C., Chen, Y. & Wang, S. (2018) 73P Ganoderic acids BT-01, a galectin-1 inhibitor, suppresses ovarian cancer growth in humanized mouse xenograft model. Annals of Oncology 29(suppl_9): mdy430. 004.

Huang, M., Wang, F., Zhou, X., Yang, H. & Wang, Y. (2015) Hypoglycemic and hypolipidemic properties of polysaccharides from Enterobacter cloacae Z0206 in KKAy mice. Carbohydrate Polymers 117: 91-98.

Jia, J., Zhang, X., Hu, Y.-S., Wu, Y., Wang, Q.-Z., Li, N.-N., Guo, Q.-C. & Dong, X.-C. (2009) Evaluation of in vivo antioxidant activities of Ganoderma lucidum polysaccharides in STZ-diabetic rats. Food Chemistry 115(1): 32-36.

Jin, Z. & Zhao, H. (2017) Comparison of the Effects of Fucoxanthin, Ganoderma lucidum Spore Powder and Lycium ruthenicum on Alcoholic Fatty Liver in Mice. Journal of Anhui Agricultural Sciences 2017(16): 34.

Kabir, Y., Kimura, S. & Tamura, T. (1988) Dietary effect of Ganoderma lucidum mushroom on blood pressure and lipid levels in spontaneously hypertensive rats (SHR). Journal of Nutritional Science and Vitaminology 34(4): 433-438.

Kang, D., Mutakin, M. & Levita, J. (2015) Computational study of triterpenoids of Ganoderma lucidum with aspartic protease enzymes for discovering HIV-1 and plasmepsin inhibitors. International Journal of Chemistry 7(1): 62.

Keypour, S., Mirzania, F. & Farimani, M.M. (2019) Antioxidant Activity, Total Flavonoid and Phenolic Contents of Three Different Extracts of Hyrcanian Reishi. Current Bioactive Compounds 15(1): 109-113.

Kimura, Y., Okuda, H. & Arichi, S. (1988) Effects of the extracts of Ganoderma lucidum on blood glucose level in rats. Planta Medica 54(04): 290-294.

Ko, Y.-F., Martel, J., Liau, J.-C., Chang, I.-T., Jian, W.-T., Mei-Feng, L., Yang, C.-J., Chiu, C.-Y., Chang, C.-J. & Lin, C.-S. (2017). Method to prepare ganoderma lucidum polysaccharides possessing protective activities on fatty liver disease: Google Patents.

Kubota, A., Kobayashi, M., Sarashina, S., Takeno, R., Okamoto, K., Narumi, K., Furugen, A., Suzuki, Y., Takahashi, N. & Iseki, K. (2018) Reishi mushroom Ganoderma lucidum Modulates IgA production and alpha-defensin expression in the rat small intestine. Journal of Ethnopharmacology 214: 240-243.

Kuo, M.-C., Weng, C.-Y., Ha, C.-L. & Wu, M.-J. (2006) Ganoderma lucidum mycelia enhance innate immunity by activating NF-κB. Journal of Ethnopharmacology 103(2): 217-222.

Lai, L.K. (2011). Development of Bioactivity-guided Purification Methods of Anti-Human Papillomavirus (HPV) 16 E6-active Compounds from Ganoderma Lucidum P. Karst. Institut Sains Biologi, Fakulti Sains, Universiti Malaya.  

Lai, L.K., Abidin, N.Z., Abdullah, N. & Sabaratnam, V. (2010) Anti-human papillomavirus (HPV) 16 E6 activity of Ling Zhi or Reishi medicinal mushroom, Ganoderma lucidum (W. Curt.: Fr.) P. Karst.(Aphyllophoromycetideae) extracts. International Journal of Medicinal Mushrooms 12(3).

Lasukova, T., Maslov, L., Arbuzov, A., Burkova, V. & Inisheva, L. (2015) Cardioprotective activity of Ganoderma lucidum extract during total ischemia and reperfusion of isolated heart. Bulletin of Experimental Biology and Medicine 158(6): 739-741.

Lawal, T.O., Wicks, S.M., Calderon, A.I. & Mahady, G.B. (2019). Bioactive Molecules, Pharmacology and Future Research Trends of Ganoderma lucidium as a Cancer Chemotherapeutic Agent New Look to Phytomedicine (pp. 159-178): Elsevier.

Li, E.K., Tam, L.S., Wong, C.K., Li, W.C., Lam, C.W., Wachtel‐Galor, S., Benzie, I.F., Bao, Y.X., Leung, P.C. & Tomlinson, B. (2007) Safety and efficacy of Ganoderma lucidum (lingzhi) and San Miao San supplementation in patients with rheumatoid arthritis: a double‐blind, randomized, placebo‐controlled pilot trial. Arthritis Care & Research 57(7): 1143-1150.

Li, F., Zhang, Y. & Zhong, Z. (2011) Antihyperglycemic effect of Ganoderma lucidum polysaccharides on streptozotocin-induced diabetic mice. International Journal of Molecular Sciences 12(9): 6135-6145.

Liang, Z., Yuan, Z., Li, G., Fu, F. & Shan, Y. (2018) Hypolipidemic, Antioxidant, and Antiapoptotic Effects of Polysaccharides Extracted from Reishi Mushroom, Ganoderma lucidum (Leysser: Fr) Karst, in Mice Fed a High-Fat Diet. Journal of Medicinal Food 21(12): 1218-1227.

Liu, Z., Xing, J., Zheng, S., Bo, R., Luo, L., Huang, Y., Niu, Y., Li, Z., Wang, D. & Hu, Y. (2016) Ganoderma lucidum polysaccharides encapsulated in liposome as an adjuvant to promote Th1-bias immune response. Carbohydrate Polymers 142: 141-148.

Luo, L., Cai, L.M. & Hu, X.J. (2014). Evaluation of the anti-hypoxia and anti-fatigue effects of ganoderma lucidum polysaccharides. Applied Mechanics and Materials, 303-306.

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Meneses-Alvarez, M., Martinez-Carrera, D., Morales, P., Sobal, M., Bernabé, T., Granados-Portillo, O., Torres, N. & Tovar, A. (2015) A Ganoderma lucidum extract derived from Mexican genetic resources and its effect on lipid metabolism gene expression and liver fatty acid composition. The FASEB Journal 29(1_supplement): 271.274.

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Mohammed, A., Adelaiye, A., Abubakar, M. & Abdurahman, E. (2007) Effects of aqueous extract of Ganoderma lucidum on blood glucose levels of normoglycemic and alloxan-induced diabetic wistar rats. Journal of Medicinal Plants Research 1(2): 034-037.

Othman, R. (2018) Immunostimulatory and Anti-inflammatory Effect of Ganoderma Lucidum on Breast Cancer Patients. Asian Pacific Journal of Cancer Biology 3(2).

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